Calico cats show a mix of orange, black, and white fur. Many people think they are all female. This idea comes from their genes. But rare cases exist. Read on to learn the details.
What Is a Calico Cat?
A calico cat has a coat with three colors. These are orange, black, and white. The colors form patches. Calico is not a breed. It is a color pattern. You can find it in many cat types.
Common breeds with calico coats include:
- American Shorthair
- Persian
- Maine Coon
- British Shorthair
- Manx
Calico cats differ from tortoiseshell cats. Tortoiseshell cats mix orange and black without white. Calico adds white spots. Both patterns link to the same genes.
For more on cat types, try our pet breed finder quiz.

Why Are Most Calico Cats Female?
Cat fur color ties to chromosomes. The genes for orange and black sit on the X chromosome. Female cats have two X chromosomes (XX). Male cats have one X and one Y (XY).
In females, one X turns off in each cell. This is X-inactivation. It creates patches of color. One patch uses the gene from one X. Another uses the other.
Males have only one X. They show one color, like all orange or all black. To get both, they need an extra X. This happens rarely.
About 99.9% of calico cats are female. This fact holds true today.
Can Male Cats Be Calico?
Yes, but it is rare. One in 3,000 calico cats is male. These males often have XXY chromosomes. This is Klinefelter syndrome. It adds an extra X.
Most male calicos cannot have kittens. They may face health problems. Some are chimeras. This means two embryos fused. One has XX cells, the other XY.
If you have a male calico, see a vet. Check for issues. Use our pet symptom checker for signs.

How Does Genetics Work in Calico Cats?
Genes control coat color. The O gene makes orange. Its pair makes black. These are on the X.
Females get one X from mom and one from dad. If mom gives orange and dad gives black, the cat shows both.
White comes from a different gene. It is not on the X. This gene adds white areas.
Dilute calico has softer colors. Gray instead of black. Cream instead of orange.
For cat health questions, read our post on how many teeth do cats have.
Do Calico Cats Have Special Traits?
Calico cats act like other cats. Some say they have strong wills. But this is a myth. Behavior depends on the cat, not color.
They live 12 to 15 years. This matches most house cats. Keep them indoors for safety.
Calico cats need the same care. Feed good food. Check our pet food safety checker.
They may link to luck in some places. In Japan, they are “maneki-neko.” These bring good fortune. Maryland named them the state cat in 2001.
Health Tips for Calico Cat Owners
Calico cats face no unique risks from color. But watch for common cat problems. These include weight gain or skin issues.
Spay females to prevent heat cycles. Learn more in how often do cats go into heat.
For males with XXY, check for heart or bone problems. Vets can test genes.
Use our pet age calculator to track your cat’s stage.

Common Questions About Calico Cats
People often ask these:
- Are all orange cats male? No. About 80% are male. Females need two orange genes.
- Why do calico cats look patchy? From random X-inactivation in cells.
- Can calico cats have kittens? Yes, females can. But not all kittens will be calico.
- What is the difference between calico and tabby? Tabby is stripes. Calico can have tabby in patches.
- Do calico cats get along with dogs? It depends on the cat. Try our pet compatibility checker.
For behavior, see why do cats knead.
Where Did Calico Cats Come From?
Calico patterns started in Egypt. Trade ships spread them. They reached Europe and Asia.
Today, they live worldwide. Adopt one from shelters. Many need homes.
Name your new calico with our pet name generator.